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Mitchell Croatt

**Expertise: Organic Chemistry, Synthetic Methods Design and Development **Education: B.S., University of Minnesota, Twin Cities, 2002--Ph.D., Stanford University, 2007-- Postdoctoral Fellow, ETH-Zurich, 2008-2010

There are 6 included publications by Mitchell Croatt :

TitleDateViewsBrief Description
The Diene Effect: The Design, Development, and Mechanistic Investigation of Metal-Catalyzed Diene-yne, Diene-ene, and Diene-allene [2+2+1] Cycloaddition Reactions 2010 329 Metal-catalyzed diene-yne, diene-ene, and diene-allene [2+2+1] cycloaddition reactions provide new methods for the facile construction of highly functionalized five-membered rings. These reactions can be conducted with a variety of substrate substitu...
Metal-Catalyzed [2+2+1] Cycloadditions of 1,3-Dienes, Allenes, and CO 2006 269 Step economy is a preeminent goal of synthesis.[1] It influences the length, efficiency, cost, time, separation, and environmental impact of a synthesis. Step economy is favored by the use of single, serial, or multicomponent reactions tha...
New reactions and step economy: the total synthesis of (±)-salsolene oxide based on the type II transition metal-catalyzed intramolecular [4 + 4] cycloaddition 2006 311 Studies on the viability of the type II nickel-catalyzed intramolecular [4+4] cycloaddition of bis-dienes show that it is influenced by both diene substitution and geometry. Both E- and Z-isomers of 19 and 20 react, albeit at markedly different rates...
Probing the Role of the Mycosamine C2'-OH on the Activity of Amphotericin B 2011 5 A synthetic route to a mycosamine donor was designed and provided access to a set of AmB derivatives targeted to probe the effect of the C2'-OH. It was determined that the configuration of the C2'-position is inconsequential but that O-methylation of...
Selective Formation of 1,5-Substituted Sulfonyl Triazoles Using Acetylides and Sulfonyl Azides 2011 3798 The reaction of acetylides with sulfonyl azides was found to selectively form 1,5-substituted sulfonyl triazoles. This reaction thus provides access to the regioisomeric product as compared to the popular copper-catalyzed azide–alkyne cycloaddition. ...
Selective Formation of 1,5-Substituted Sulfonyl Triazoles Using Acetylides and Sulfonyl Azides 2011 11 The reaction of acetylides with sulfonyl azides was found to selectively form 1,5-substituted sulfonyl triazoles. This reaction thus provides access to the regioisomeric product as compared to the popular copper-catalyzed azide–alkyne cycloaddition. ...