Maria Elena Meza-Avina

There are 4 included publications by Maria Elena Meza-Avina :

TitleDateViewsBrief Description
Alkynes and Azides: Not Just for Click Reactions. 2012 1982 We recently reported two unexplored reactivities of alkynes and azides. The first method reacts nucleophilic alkynes and electrophilic azides to synthesize sulfonyl-substituted 1,5-disubstituted-1,2,3-triazoles. The second method reacts electrophili...
Exploring the reactivity of 1,5-disubstituted sulfonyl-triazoles: Thermolysis and Rh(II)-catalyzed synthesis of a-sulfonyl nitriles 2013 1403 The reactivity of a series of 1,5-disubstituted sulfonyl-triazoles was explored using either thermolytic or metal-catalyzed conditions. Both the thermolysis and the Rh(II)-catalyzed reactions led to the synthesis of a-sulfonyl-nitriles, which presuma...
Selective Formation of 1,5-Substituted Sulfonyl Triazoles Using Acetylides and Sulfonyl Azides 2011 1797 The reaction of acetylides with sulfonyl azides was found to selectively form 1,5-substituted sulfonyl triazoles. This reaction thus provides access to the regioisomeric product as compared to the popular copper-catalyzed azide‚Äďalkyne cycloaddition. ...
Structural Determinants for the Inhibitory Ligands of Orotidine-5'-Monophosphate Decarboxylase 2010 1021 In recent years, orotidine-5'-monophosphate decarboxylase (ODCase) has gained renewed attention as a drug target. As a part of continuing efforts to design novel inhibitors of ODCase, we undertook a comprehensive study of potent, structurally diverse...