Browse All

Theses & Dissertations

Submissions

Katula, Karen

uncg

There are 8 item/s.

TitleDateViewsBrief Description
The Effect of Folate Deficiency on the Wnt Signaling Pathway 2008 827 Folate is an essential dietary vitamin involved in methylation reactions and DNA synthesis. Insufficient dietary folate has been associated with various developmental and adult diseases such as neural tube defects and colorectal cancer. The basis for...
Effects of altered folate metabolism on specific gene expression in the developing Xenopus embryo 2006 889 "Approximately 1 out of every 2000 births in the United States is affected by neural tube defects. The most well-known environmental cause of neural tube malformation is folate deficiency in pregnant women. The underlying mechanism for this relation...
Regulation of dickkopf-1(Dkk-1) promoter sequences under various growth conditions 2006 905 "The goal of this study was to determine what region of the Dkk-1 promoter was required for expression of the Dkk-1 gene under different growth conditions. Dkk-1 promoter activity was analyzed in NIH3T3 cell lines stably transfected with luciferase ...
Possible involvement of NF-?B in the response of cells to folate deficiency. 2009 238 Folate, a water soluble B vitamin, serves as a methyl donor for the synthesis of nucleotides and methionine. Folate deficiency has been linked to a variety of health problems that include developmental defects, cancer and neurological diseases. The r...
The Effects of Folate Deficiency on on E-cadherin and ß-catenin in Colon Epithelial Cells 2009 433 Folate deficiency has been linked to multiple health problems including neural tube defects and cancer, especially colorectal cancer. Folate is an essential dietary vitamin that is required for DNA synthesis and cellular methylation reactions. The me...
The effects of folate deficiency on E-cadherin and ß-catenin in colon epithelial cells. 2009 433 Folate deficiency has been linked to multiple health problems including neural tube defects and cancer, especially colorectal cancer. Folate is an essential dietary vitamin that is required for DNA synthesis and cellular methylation reactions. The me...
Characterization and regulation of Wnt5a alternate promoters A and B 2011 947 WNT5A is an extracellular glycoprotein that activates several Wnt signaling pathways important in cancer. Significantly, Wnt5a expression is altered in numerous cancers. Little is known about Wnt5a gene regulation but current data indicate that misre...
Expression of Wnt5a alternative promoters A and B during cancer progression and cellular differentiation 2012 430 WNT5A is a secreted glycoprotein that plays an important role in cellular differentiation, cell homeostasis and development. It is also misregulated in numerous cancer cell types. The Wnt5a gene generates multiple transcripts from distinct promoters ...