Dose-response effects of aerobic exercise on adiposity markers in postmenopausal women: pooled analyses from two randomized controlled trials

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Jessica McNeil, Assistant Professor (Creator)
The University of North Carolina at Greensboro (UNCG )
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Abstract: Background/objective: Exercise may reduce the risk of breast cancer through adiposity changes, but the dose-response effects of exercise volume on adiposity markers are unknown in postmenopausal women. We aimed to compare the dose-response effects of prescribed aerobic exercise volume on adiposity outcomes. Participants/methods: Data from the Alberta Physical Activity and Breast Cancer Prevention (ALPHA) and Breast Cancer and Exercise Trial in Alberta (BETA) were pooled for this analysis (N?=?720). These were 12-month randomized controlled trials, where participants were randomized to 225?min/week (mid-volume) of aerobic exercise versus usual inactive lifestyle (ALPHA), or 150?min/week (low-volume) versus 300?min/week (high-volume) (BETA). Fat mass and fat-free mass were measured using DXA and intra-abdominal and subcutaneous fat area were assessed with computed tomography. Results: After 12 months of aerobic exercise, increasing exercise volumes from no exercise/control to 300?min/week resulted in statistically significant reductions in BMI, weight, fat mass, fat percentage, intra-abdominal and subcutaneous fat area (P?

Additional Information

International Journal of Obesity
Language: English
Date: 2021
postmenopausal, breast cancer risk, exercise, adiposity

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