Incidence of Vancomycin Resistant Enterococci (VRE) colonization in adult hematopoietic stem cell transplant (HSCT) patients after discontinuation of isolation precautions

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Mary Lauren Green (Creator)
Institution
The University of North Carolina at Greensboro (UNCG )
Web Site: http://library.uncg.edu/
Advisor
Julia Kordsmeier

Abstract: Background: Vancomycin-resistant enterococcus (VRE) is a leading cause of hospital acquired infection and a major cause of bacteremia among hematopoietic stem cell transplant (HSCT) patients. To prevent the transmission of VRE colonization, many institutions employ contact isolation precautions including gown and glove for contact with patients that are VRE colonized. This practice is based on guidelines from the Centers for Disease Control and Prevention (CDC) which are outdated and do not reflect recent studies that demonstrate no adverse effects of discontinuation of contact isolation on the incidence of VRE colonization. Purpose: To determine if there was significant change in the incidence of VRE colonization after institutional practice change that temporarily suspended routine contact isolation precautions for VRE colonized patients.Methods: The incidence of VRE colonization was measured retrospectively in Adult HSCT patients during two different 3-month time periods; the first during active use of contact isolation and the second after discontinuation of contact isolation. Results: The incidence of VRE colonization remained stable after discontinuation of contact isolation precautions of VRE colonized patients.Conclusion: Discontinuation of contact isolation precautions in VRE colonized patients did not appear to increase the incidence of VRE colonization in adult HSCT patients. The project site continues to practice without contact isolation for VRE colonized patients.

Additional Information

Publication
Dissertation
Language: English
Date: 2022
Keywords
Vancomycin-resistant enterococci, contact isolation, adults, hematopoietic stem cell transplant or bone marrow transplant, personal protective equipment, COVID-19, personal protective equipment, shortage

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