WD Repeat Domain of Dictyostelium Myosin Heavy Chain Kinase C Functions in both Substrate Targeting and Cellular Localization
- UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
- Paul A. Steimle, Assistant Professor (Creator)
- Institution
- The University of North Carolina at Greensboro (UNCG )
- Web Site: http://library.uncg.edu/
Abstract: Myosin II disassembly in Dictyostelium discoideum is regulated by three structurally related myosin heavy chain kinases (myosin II heavy chain kinase A [MHCK-A], -B, and -C). We show that the WD repeat domain of MHCK-C is unique in that it mediates both substrate targeting and subcellular localization, revealing a target for regulation that is distinct from those of the other MHCKs.
WD Repeat Domain of Dictyostelium Myosin Heavy Chain Kinase C Functions in both Substrate Targeting and Cellular Localization
PDF (Portable Document Format)
236 KB
Created on 1/1/2010
Views: 1894
Additional Information
- Publication
- Eukaryotic Cell, 9:344-349
- Language: English
- Date: 2010
- Keywords
- Myosin II disassembly, Dictyostelium discoideum, myosin heavy chain kinases