Palladium-Catalyzed Chemoselective Protodecarboxylation of Polyenoic Acids
- UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
- Mohammed Al-Huniti, Research Scientist (Creator)
- Mitchell Croatt, Assistant Professor (Creator)
- Institution
- The University of North Carolina at Greensboro (UNCG )
- Web Site: http://library.uncg.edu/
Abstract: Conditions for the first palladium-catalyzed chemoselective protodecarboxylation of polyenoic acids to give the desired polyenes in good yields are presented. The reactions proceed under mild conditions using either a Pd(0) or Pd(II) catalyst and tolerate a variety of aryl and aliphatic substitutions. Unique aspects of the reaction include the requirement of phosphines, water, and a polyene adjacent to the carboxylic acid.
Palladium-Catalyzed Chemoselective Protodecarboxylation of Polyenoic Acids
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Created on 2/19/2019
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Additional Information
- Publication
- Organic Letters 2018, 23, 7375-7379
- Language: English
- Date: 2018
- Keywords
- Polyenoic Acids, Protodecarboxylation