Oleanolic Acid, a Bioactive Component of the Leaves of Ocimum Gratissimum (Lamiaceae)
- UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
- Nicholas Oberlies, Patricia A. Sullivan Distinguished Professor of Chemistry (Creator)
- Institution
- The University of North Carolina at Greensboro (UNCG )
- Web Site: http://library.uncg.edu/
Abstract: Bioactivity-guided fractionation of the leaves of Ocimum gratissimum L. (Lamiaceae), using the brine shrimp lethality test, led to the isolation of oleanolic acid. Oleanolic acid showed bioactivity against a panel of six human solid tumor cell lines, the nematode Caenorhabditis elegans and yellow fever mosquito larvae Aedes aegypti. Details of the isolation and bioactivities are described.
Oleanolic Acid, a Bioactive Component of the Leaves of Ocimum Gratissimum (Lamiaceae)
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Additional Information
- Publication
- International Journal of Pharmacognosy, 35:2, 134-137, DOI: 10.1076/phbi.35.2.134.13290
- Language: English
- Date: 1997
- Keywords
- Aedes aegypti, brine shrimp test, Caenorhabditis elegans, cytotoxicity, Ocimum gratissimum, oleanolic acid, yellow fever mosquito