Oleanolic Acid, a Bioactive Component of the Leaves of Ocimum Gratissimum (Lamiaceae)

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Nicholas Oberlies, Patricia A. Sullivan Distinguished Professor of Chemistry (Creator)
The University of North Carolina at Greensboro (UNCG )
Web Site: http://library.uncg.edu/

Abstract: Bioactivity-guided fractionation of the leaves of Ocimum gratissimum L. (Lamiaceae), using the brine shrimp lethality test, led to the isolation of oleanolic acid. Oleanolic acid showed bioactivity against a panel of six human solid tumor cell lines, the nematode Caenorhabditis elegans and yellow fever mosquito larvae Aedes aegypti. Details of the isolation and bioactivities are described.

Additional Information

International Journal of Pharmacognosy, 35:2, 134-137, DOI: 10.1076/phbi.
Language: English
Date: 1997
Aedes aegypti, brine shrimp test, Caenorhabditis elegans, cytotoxicity, Ocimum gratissimum, oleanolic acid, yellow fever mosquito

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