Wei Zhong

  • Research Scientist
  • Center for Translational Biomedical Research, UNCG
  • w_zhong@uncg.edu
  • North Carolina Research Campus Suite 4226

Dr. Zhong’s research interests are organ-organ interactions at the gut-liver-adipose tissue axis in the pathogenesis of alcoholic and nonalcoholic liver disease. She focuses her research on the roles of nutritional elements and gut microbiota in alcohol metabolism and whole body energy homeostasis. Outcomes of these studies are important to understand the mechanisms involved in the pathogenesis of alcoholic and nonalcoholic liver disease. Dr. Zhong received her Ph.D. degree in Veterinary Biomedicine from China Agricultural University, China. She earned her B.A. degree in Veterinary Medicine from Northwest Agriculture and Forestry University, China.

There are 5 included publications by Wei Zhong :

TitleDateViewsBrief Description
Chronic Alcohol Exposure Disturbs Lipid Homeostasis at the Adipose Tissue-Liver Axis in Mice: Analysis of Triacylglycerols Using High-Resolution Mass Spectrometry in Combination with In Vivo Metabolite Deuterium Labeling 2013 741 A method of employing high-resolution mass spectrometry in combination with in vivometabolite deuterium labeling was developed in this study to investigate the effects of alcohol exposure on lipid homeostasis at the white adipose tissue (WAT)-liver a...
Effects of Toosendanin on Pregnancy and Uterine Immunity Alterations in Mice 2010 944 This study was conducted to explore the abortifacient effect and the mechanisms of the Chinese herbal medicine component toosendanin, and to elucidate the significance of the Th1 cytokines IFN-gamma and TNF-alpha, CD4+ and CD8+ T lymphocytes in the o...
MFG-E8 and HMGB1 Are Involved in the Mechanism Underlying Alcohol-Induced Impairment of Macrophage Efferocytosis 2013 1127 Efferocytosis is a unique phagocytic process for macrophages to remove apoptotic cells in inflammatory loci. This event is maintained by milk fat globule-EGF factor 8 (MFG-E8), but attenuated by high mobility group box 1 (HMGB1). Alcohol abuse causes...
Zinc and Hepatocyte Nuclear Factor-4a in Alcohol-Induced Intestinal Barrier Dysfunction 2012 1283 Zinc is an essential micronutrient and plays an important role in maintaining intestinal epithelial integrity. Increasing evidence support that zinc homeostasis has significant impact on the intestinal barrier via regulation of epithelial tight junct...
Zinc Supplementation Reverses Alcohol-induced Steatosis in Mice Through Reactivating Hepatocyte Nuclear Factor-4a and Peroxisome Proliferator-activated Receptor-a 2009 841 Alcoholic steatosis is a fundamental metabolic disorder in the progression of alcoholic liver disease. Zinc deficiency is one of the most consistently observed biochemical/nutritional manifestations of alcoholic liver disease. The purpose of this stu...