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Theses & Dissertations


Marinella Sandros

Prof. Sandros research concentration is focused on the integration of inorganic nanomaterials and polymers with biology. She has previously designed a reagentless protein-based nanobiosensor for selective small molecules detection using conformational dependent interactions between a redox active metal complex ion RuII and the surface of a CdSe nanoparticle. Prof Sandros was able to enhance the biointerface properties of InGaP@ZnS quantum dots by encapsulating them in chitosan. Along with her collaborators, she has developed a robust and stable multifunctional siRNA delivery system and amplified Surface Plasmon Resonance Imaging (SPRi) signals using nanoparticles. Prof. Sandros future research goals aim at: 1. Developing novel nano-imaging probes with enhanced biointerfacing properties for deep tissue imaging. 2. Engineering a highly integrated platform that allows for molecular diagnosis targeted drug delivery, and simultaneous monitoring and treatment of cardiovascular diseases. 3. Introducing new methods to enhance the sensitivity of SPRi technology for medical diagnostic.