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Theses & Dissertations


Steimle, Paul


There are 3 item/s.

TitleDateViewsBrief Description
An analysis of the mechanism of Dictyostelium myosin II heavy chain kinase B in substrate targeting 2009 559 Previous studies have shown that myosin heavy chain kinase A and B (MHKA and MHKB) are able to phosphorylate and disassemble Dictyostelium discoideum myosin II bipolar filaments by directly targeting myosin II via a conserved region of WD repeats, al...
Studies of the Actin Binding Activity of Dictyostelium discoideum Myosin II Heavy Chain Kinase A. 2008 465 Dictyostelium discoideum is a primitive, eukaryotic organism that relies on myosin II and actin contraction for cytokinesis, migration, and other important cellular processes. In order for contraction to occur, myosin II monomers must first assemble ...
Cloning & Cellular Characterization of Myosin II Heavy Chain Kinase D from Dictyostelium discoideum. 2008 585 The thesis research presented here focused on studies of a novel myosin II heavy chain kinase D (MHCK D) expressed in Dictyostelium discoideum cells. MHCK D is made up of four distinct domains: a short coiled-coil region (Coil), a region rich in seri...