McIntosh, Michael

uncg

There are 10 item/s.

TitleDateViewsBrief Description
Impact of the HEROS (Healthy Eating to Reduce Obesity through Schools) study on healthy food choices and obesity among middle school students in Guilford County (NC) schools 2005 14735 "The prevalence of overweight among adolescents in the U.S. has increased rapidly over the past two decades. This problem is closely related to poor dietary behaviors. Two preliminary, school-based studies were conducted in Guilford County Schools, w...
Impact of trans-10, cis-12 conjugated linoleic acid on interleukin (IL)-6 and IL-8 and adipogenic genes in cultures of human adipose tissue explants 2005 1608 "Obesity has reached epidemic proportions in the United States, currently ranking second among causes of preventable deaths. Our research group has shown in cultures of differentiated human adipocytes that 30 uM trans-10, cis-12 Conjugated Linoleic ...
Mechanisms by which conjugated linoleic acid causes human adipocyte delipidation 2006 2175 "Obesity is an important health issue, having risen to epidemic proportions in the U.S. Use of conjugated linoleic acid (CLA), positional and geometric isomers of linoleic acid, has received recent attention due to its potential health benefits inclu...
The antiobesity mechanism of conjugated linoleic acid 2009 3613 Given the steady rise in obesity worldwide, it is important to identify dietary compounds that prevent adiposity. One dietary strategy is supplementation with conjugated linoleic acid (CLA), which has been demonstrated to reduce body fat mass. Howeve...
Grape powder extract (GPE) attenuates markers of inflammation in human macrophages. 2010 1662 Obesity is linked to chronic inflammation in white adipose tissue (WAT) which is exacerbated by infiltrating macrophages (MΦ)s. Grape powder extract (GPE) contains polyphenols that have the potential to prevent this inflammatory response that c...
Conjugated linoleic acid (CLA) promotes inflammation to a greater extent in human adipocytes compared to preadipocytes 2011 4881 Due to the increasing prevalence of obesity and diabetes among children and adults worldwide, it is imperative to identify dietary strategies that promote weight control. One potential anti-obesity compound is conjugated linoleic acid (CLA), sold wor...
Grape polyphenols attenuate inflammation and insulin resistance in human adipocytes and obese mice 2012 8033 Obesity is rapidly increasing worldwide among all age groups. Insulin resistance or type 2 diabetes is one of several debilitating health problems associated with obesity. An emerging feature of obesity and type 2 diabetes is their linkage with chron...
Impact of California table grapes on systemic inflammation, insulin resistance, and hepatic steatosis in mice fed an American-type diet 2015 506 The incidence of obesity is increasing worldwide, currently affecting over 400 million people. With obesity, expansion of white adipose tissue (WAT) contributes to a chronic, low-grade inflammatory response that is associated with the formation of co...
The impact of California table grapes on intestinal inflammation and microbiota in mice fed an american type diet 2015 700 Obesity is a growing health concern in the United States and worldwide. The chronic, low grade inflammation associated with increased white adipose tissue mass has been linked to chronic metabolic disorders such as insulin resistance, hypertension, a...
Anti-obesity mechanisms of conjugated linoleic acid (CLA): role of inflammatory signaling and browning in white adipose tissue 2015 1027 Overweight and obesity are the most widespread nutritional diseases in the U.S., which greatly increase chronic disease risks and mortality. Therefore, it is urgent to develop a relatively efficacious and safe strategy for the weight management. Cons...