Erikson, Keith

uncg

There are 8 item/s.

TitleDateViewsBrief Description
Effects of manganese exposure and iron deficiency on the biology of GABA and norepinephrine 2009 814 Both manganese (Mn) and iron (Fe) are dietary metals required for numerous important processes in mammalian systems, and disturbances in the homeostasis of these metals can have deleterious effects, specifically on the central nervous system. In thes...
Effects of manganese exposure and antioxidant therapy on oxidative stress and stereotypic behaviors in rats 2009 3574 Manganese (Mn) is an essential dietary element required for several important physiological processes. However, accumulation of Mn due to excessive environmental exposure is known to pose neurological health concerns that manifest as movement abnorma...
Creatine as a neuroprotective agent in manganese-induced neurotoxicity 2011 5547 Manganese (Mn) is a trace metal that is essential for optimal functioning of mammalian systems. However, excessive exposure to Mn is known to cause an extrapyramidal disease. Presently, Mn-induced neurotoxicity has no cure. In these studies, we exami...
The effect of manganese neurotoxicity on the Gamma-Aminobutyric acid (GABA) neurotransmitter system 2013 890 Manganese (Mn) is an essential metal that functions primarily as a cofactor for metalloenzymes contributing to numerous metabolic pathways. Exposure to excess environmental Mn overwhelms endogenous regulation, and deleterious effects disrupt neurotra...
The effects of dietary-induced obesity on regional brain iron biology 2014 721 Iron is an essential dietary element that supports oxygen transport, nutrient metabolism and protein synthesis; however, dysregulation of iron biology can be detrimental to health. The importance of iron homeostasis is particularly apparent in the br...
The influence of sex and strain on neurobiological and behavioral changes due to diet-induced obesity 2020 51 Diet-induced obesity (DIO) is linked to several adverse neurobiological and behavioral changes, including altered trace element homeostasis, dysregulated dopamine biology, increased anxiety, and reduced physical activity. These DIO-associated harmful...
The effects of diet-induced obesity on the distribution of systemic trace elements 2020 45 Background: Iron, copper, manganese, and zinc are essential trace elements critical for cellular and physiological process, such as catalytic enzymatic reactions, gene regulation, and signaling cascades. These elements must be maintained through home...
The consequences of putative inflammation on brain trace metal biology 2022 23 Manganese, copper, and iron are essential trace metals necessary for proper functioning of the human body, and play important roles in cellular responses, signaling, regulation, and overall cell function and metabolism, making them necessary for norm...