Reddick, Jason

uncg

There are 16 item/s.

TitleDateViewsBrief Description
Characterization of PksD and PksG in Bacillus subtilis 2006 2119 Polyketides are a diverse class of natural products that have a wide variety of pharmacological applications. Polyketides are biosynthesized by modular polyketide synthases in a very similar fashion to that of fatty acids. The distinct features of ea...
Characterization of PksS in Bacillus subtilis 2007 2177 "Cytochrome P450s are a common type of the polyketide tailoring enzymes that are responsible for the hydroxylation of polyketides. PksS, a likely tailoring enzyme, is found within the gene cluster pksX, from Bacillus subtilis. The gene cluster was fo...
a A convergent and modular synthesis of dienyl and diynyl isobutylamide natural products from echinacea and spilanthes herbal medicines 2007 4386 ""Echinacea" and "Spilanthes" are popular over-the-counter herbal supplements derived from raw tissue or tissue extracts from plants such as Echinacea purpurea and Spilanthes acmella, respectively. Several chemical constituents have been identified a...
Overexpression, purification, and characterization of AcpK, PksG, and MmgA from Bacillus subtilis strain 168 2007 2186 AcpK, Sfp, PksG, and MmgA were successfully overexpressed and purified from B. subtilis 168, and a donated overexpression vector. PPT reactions with Sfp and AcpK were successfully performed. Biochemical characterization of PksG was carried out and de...
Overexpression, Purification, and Characterization of MmgB and MmgC from Bacillus subtilis Strain 168. 2008 2334 For years, developmental biology has been in search of an understanding as to how an organism undergoes cellular differentiation to produce distinct cell types. Bacillus subtilis is a bacterial organism that undergoes cellular differentiation during ...
Overexpression, purification, and characterization of MmgD from Bacillus subtilis strain 168. 2009 1537 Bacillus subtilis, a rod shaped gram-positive bacterium, is highly studied because of its capability of forming endospores when there is an inadequate supply of nutrients. Despite the lack of nutrients in the environment, this microorganism has to be...
Characterization of biosynthetic and catabolic pathways of Bacillus subtilis strain 168. 2009 2926 Bacillus subtilis has long been a model bacterium for understanding biological mechanisms, such as fatty acid catabolism and polyketide biosynthesis. Our interest in the latter was centered on the polyketide synthase (PKS) mechanism responsible for ß...
Analysis of a possible multienzyme complex encoded by mother cell metabolic gene (mmg) operon of Bacillus subtilis strain 168. 2010 2160 Bacillus subtilis is a rod shaped, aerobic, endospore forming gram-positive bacterium. B. subtilis is used as a model organism to study cell differentiation during sporulation in prokaryotes. When there is inadequate supply of carbon resources, B. su...
Characterization of the biochemical activity of the open reading frame "YqiQ" of Bacillus subiltilis 2011 2018 The goal of this research is to provide a greater chemical understanding of the mechanisms by which Bacillus subtilis transforms itself into a spore during times of nutrient deprivation. The area of interest of this study lies in the mother cell meta...
Biochemical characterization of MmgB, a gene encoding a 3-Hydroxybutyryl-CoA dehydrogenase from bacillus subtilis 168 and genetic evidence for the methylcitric acid cycle in bacillus subtilis 168 2011 91 Bacillus subtilis is an industrially important organism because of its ability to produce enzymes and antibiotics on a commercial scale. It is considered the Gram positive counterpart of E. coli in terms of its genetic and molecular biological access...
The characterization of mmgE from Bacillus subtilis 2012 1755 Bacillus subtilis is a rod shaped gram-positive bacterium that has been extensively studied for decades. The scientific interest lies, in large part, to its use as a model organism for the study of sporulation, which is a simple form of cell differen...
Characterization of citB in the methylcitric acid cycle of Bacillus subtilis 168 ; and, characterization of antimicrobial activity in the mucosal epithelial layer and gill tissue of largemouth bass (Micropterus salmoides) 2014 681 Bacillus subtilis 168 is a gram-positive, aerobic, rod shaped bacteria that has the ability to undergo sporulation when under nutritional stress. There is an incomplete understanding of the metabolic pathways in B. subtilis
Studies on the synthesis of threo 2-methylisocitrate 2014 702 Bacillus subtilis is the gold standard organism for Gram-positive bacteria, just as Escherichia coli is it for Gram-negative bacteria. Its genome has been fully sequenced, yet not all of its genes have been characterized. One of these genes, yqiQ, is...
Purification and characterization of an enoyl-coA hydratase encoded by the yhaR gene from Bacillus subtilis strain 168 2015 763 Bacillus subtilis is widely used as a model organism for the study of sporulation. While its genome has been sequenced, the function of many encoded proteins have not been investigated. The mother cell metabolic gene (mmg) operon is an example that c...
Investigation and comparison of stereoisomer products of 2-methylcitrate synthase and 2-methylcitrate dehydratase in Escherichia coli strain K12 and Bacillus subtilis strain 168 2017 368 Bacillus subtilis has been extensively studied and serves as a model organism for Gram-positive bacteria which can be attributed to its capacity to be genetically manipulated, form endospores, and a sequenced genome. B. subtilis undergoes a dispropor...
Towards the stereoselective syntheses of 2-methylcitrate and 2-methylisocitrate and their use in studying the methylcitric acid cycle in Bacillus subtilis 2018 3 Bacillus subtilis is a model organism and the entire genome has been sequenced. However, there is an incomplete understanding of the metabolic pathways that are encoded within the genome. A long-term goal of the Reddick research group is to gain a mo...