LaJeunesse, Dennis

uncg

There are 16 item/s.

TitleDateViewsBrief Description
Analysis of mitochondria morphology dynamics during adipogenesis 2007 3674 "There is great concern with an increase in the number of Americans who are overweight and obese. Fat cells or adipocytes play a central role in obesity. These cells are metabolically active and play a fundamental role in energy allocation and storag...
The Lettuce Head Cells of the SCANS region of the Drosophila larval midgut are required for larval midgut peristalsis. 2008 2696 The alimentary canal of the Drosophila larva is essential for survival of the organism. The gut tube is an intricate network of tissues interacting with the parasympathetic nervous system. The midgut, the region of the Drosophila gut that has the la...
Developmental characteristics of a novel cell type in the larval midgut of Drosophila melanogaster 2011 5905 In the Drosophila larval midgut, the development pathways associated with the specialized cell types found in the middle midgut region have been well characterized. In this region determination between the cell types is dependent on ...
Chitin nanofiber alignment: optical and quantitative analysis 2014 3619 Polymers are an important material in modern life. Most of our modern world is made of polymeric materials. When we think of polymers, the synthetic plastics we use on a regular basis typically come to mind, but not all polymers are synthetics. The n...
At the interface: biotic-abiotic interactions between substrates and a model epithelium 2015 995 The need for determining the fundamental mechanisms that define the interaction of biological systems with underlying materials, both natural and synthetic, is important as humanity endeavors to improve the quality of life of individuals through tech...
A bioinspired approach to the generation of novel antimicrobial materials 2016 1406 Advancements in particle beam microscopy have allowed scientists to discover a wealth of surface architectures with nanoscale dimensions, many of which endow the surfaces with fascinating properties. Investigations of such surfaces have revealed some...
High resolution visualization and characterization of cell surface adhesion protein in three-dimensional nanoscale interphases 2018 298 This dissertation studies microbial adhesion to surfaces using high magnification scanning particle beam microscopy. To study the interaction with the wings of cicada insects as our main surface of interest, the microbial model Saccharomyces cerevisi...
Synthesis and characterization of bacterial cellulose towards osteogenic differentiation of stem cells 2019 212 The extracellular matrix provides physical support and functional microenvironment in which cells exist for healthy tissue formation and maintenance. This dynamic interplay between the extracellular matrix and cells have significant effect on cellula...
Microbial interactions with nanoscale features 2019 635 Bacteria and other microbes interact with their environment through nanoscale mechanical and chemical processes. Understanding these interactions is critical for controlling bacteria, both in preventing biofilm formation and in using these interactio...
Tackling drug resistant pathogenic fungi through antimicrobial nanostructured surfaces 2020 227 Candida albicans is a common member of the human gut, skin and mucosal microbiomes. Systemic C. albicans infections are of special concern for immunocompromised patients such transplant recipients and AIDS patients. Drug resistant strains of C. albic...
Defining nanoscale genetic interactions between the bacterium E. coli and engineered nanoparticles for biomedical and environmental remediation applications 2023 260 The production of engineered nanoparticles is on the rise worldwide. Engineered nanoparticles have distinct physicochemical properties which enable their utilization in a variety of sectors from Biomedicine to Environmental remediation. Engineered na...
Nanostructure-biofilm interactions : a study of Candida albicans biofilm behaviors on different polymer surfaces with nanoscale surface modifications 2023 279 There are over a million fungal species on earth and only 300 of them are known to mankind. The dimorphic fungus, Candida albicans, is a part of the human microbiome. It is normally found in the mouth, gastrointestinal tract, and skin. Under normal c...
Mechanical evaluation of various geometrical designs in additive manufacturing for future knee brace harness 2024 35 Additive manufacturing, commonly known as 3D printing, revolutionizes the realization of computer-aided designs (CAD) by layer-by-layer printing of prototypes or objects, emulating traditional modeling techniques. Also, according to ASTM standards, a...
Bio-mimetic multimodal nanostructured surfaces fabricated with self-assembling biopolymer and its applications 2017 690 Nanotechnology will revolutionize the industrial world in 21st century. Almost every country has invested in research to unfold the mysteries of nanomaterials and for their applications. A major driving force of nanomaterial research is through the i...
Study of nanoscale structural biology using advanced particle beam microscopy 2015 1827 This work investigates developmental and structural biology at the nanoscale using current advancements in particle beam microscopy. Typically the examination of micro- and nanoscale features is performed using scanning electron microscopy (SEM), but...
Nanostructured surface induced transcriptome response in Candida albicans 2022 110 Candida albicans (C. albicans) is an opportunistic fungal pathogen, which causes superficial to systemic infections in immunocompromised patients. This pathogen produces various responses under different environmental/mechanical conditions that leads...