Neuropsychological functioning in individuals at-risk for schizophrenia : a multidimensional investigation of attention, executive functioning, and memory

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
James T. Chok (Creator)
Institution
The University of North Carolina at Greensboro (UNCG )
Web Site: http://library.uncg.edu/
Advisor
Thomas R Kwapil

Abstract: "Schizophrenia is currently conceptualized as a neurodevelopmental disorder in which subtle brain dysmaturation is expressed across a continuum of impairment referred to as schizotypy. Recently, schizophrenia researchers have attempted to identify markers that are present during all stages of the illness, as well as in subclinical manifestations of the disorder. The discovery of markers for schizophrenia should enhance our knowledge about the etiology and development of the disorder, as well as facilitate the identification of individuals at increased risk for developing the disorder. Neuropsychological impairment has long been recognized as a central feature of schizophrenia. Furthermore, neuropsychological impairment has been purported to be present before the onset of schizophrenia and indicative of liability for the disorder. The present study examined the relationship of attention, executive functioning, and memory with ratings of positive and negative schizotypy in a sample of 156 college students. Results indicated that positive schizotypy was associated with neuropsychological deficits, above and beyond the variance associated with intellectual functioning and general psychological distress. Surprisingly, negative schizotypy was not related to impaired neuropsychological performance. "--Abstract from author supplied metadata.

Additional Information

Publication
Dissertation
Language: English
Date: 2006
Keywords
Schizophrenia, neurodevelopmental, disorder, brain dysmaturation, impairment, schizotypy, researchers, markers, illness, subclinical manifestations
Subjects
Schizophrenia--Diagnosis
Schizotypal personality disorder
Attention