COMT and anxiety and cognition in children with chromosome 22q11.2 deletion syndrome
- UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
- Thomas R. Kwapil, Associate Professor (Creator)
- Institution
- The University of North Carolina at Greensboro (UNCG )
- Web Site: http://library.uncg.edu/
Abstract: The COMT gene is thought to contribute to the cognitive/psychiatric phenotypes in 22q11.2 deletion syndrome. We measured these manifestations against the Val/Met alleles of the COMT gene, in 40 nonpsychotic 22q11DS children. The Val allele was associated with poor IQ, processing speed, executive function and a higher frequency of anxiety disorders, underscoring the importance of the COMT gene in the childhood psychopathology in 22q11DS.
COMT and anxiety and cognition in children with chromosome 22q11.2 deletion syndrome
PDF (Portable Document Format)
128 KB
Created on 10/11/2012
Views: 2435
Additional Information
- Publication
- Language: English
- Date: 2010
- Keywords
- velocardiofacial syndrome, COMT Val/Met, psychopathology, psychology