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Socioeconomic Status and Psychological Function in Children with Chromosome 22q11.2 Deletion Syndrome: Implications for Genetic Counseling

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Jessica Kaczorowski (Creator)
Thomas R. Kwapil, Associate Professor (Creator)
Institution
The University of North Carolina at Greensboro (UNCG )
Web Site: http://library.uncg.edu/

Abstract: The purpose of this study is to examine the association between parental socio-economic status (SES) and childhood neurocognition and behavior in children with chromosome 22q11.2 deletion syndrome (22q11DS). Although undoubtedly, the deletion of genes in the 22q11.2 interval is primarily responsible for the psychological manifestations, little is known about the role of the environment in either mitigating or contributing to these problems. We examined the association of parental socio-economic status (SES) with cognition and behavior in children with 22q11DS (n?=?65) and matched healthy control subjects (n?=?52), since SES is a component of family resources. We found that in children with 22q11DS, higher SES correlated with better overall functioning (p?

Additional Information

Publication
Journal of Genetic Counseling, 19, 535-544
Language: English
Date: 2010
Keywords
22q11.2 deletion syndrome, Velocardiofacial syndrome, DiGeorge syndrome, SES, Neurocognition, Psychopathology