Photostimulation Alters c-Fos Expression In The Dorsal Raphe Nucleus
- ASU Author/Contributor (non-ASU co-authors, if there are any, appear on document)
- Dr.. Andrew Bellemer, Assistant Professor, Molecular Neuroscience (Creator)
- Institution
- Appalachian State University (ASU )
- Web Site: https://library.appstate.edu/
Abstract: Retinal afferents to the dorsal raphe nucleus (DRN) have been described in a number of species, including Mongolian gerbils, but functional correlates of this optic pathway are unknown at present. To determine whether temporally modulated photostimulation can affect c-Fos expression in the gerbil DRN, quantitative analysis of c-Fos-immunoreactive (c-Fos-ir) neurons was conducted following 60-min exposure to pulsed (2 Hz) photostimulation at selected times over the 12:12 h light/dark cycle. For comparison, c-Fos expression was also analyzed in the subnuclei of the lateral geniculate complex and in the suprachiasmatic nucleus (SCN). In the DRN, a substantial reduction was observed in the number of c-Fos immunoreactive (c-Fos-ir) neurons during the light period and early dark period in photostimulated vs. control animals. Similar results were obtained in the intergeniculate leaflet (IGL) and ventral lateral geniculate (VLG).
Photostimulation Alters c-Fos Expression In The Dorsal Raphe Nucleus
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Created on 1/10/2023
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Additional Information
- Publication
- Fite, K., Wu, P., and Bellemer, A. (2005). Photostimulation alters c-Fos expression in the dorsal raphe nucleus. Brain Research, Volume 1031, Issue 2, 21 January 2005, Pages 245-252. Publisher version of record available at: https://doi.org/10.1016/j.brainres.2004.10.054
- Language: English
- Date: 2005
- Keywords
- Immediate early gene expression,
Rodent visual system,
Lateral geniculate nucleus,
Intergeniculate leaflet,
Ventral lateral geniculate