Dr. Andrew Bellemer

RECAPP 2019 Award Winner. Education: Ph.D. Yale University Interdepartmental Neuroscience Program, New Haven, CT; B.S. University of Massachusetts, Amherst, MA. Professional Experience: Assistant Professor, Appalachian State University, Department of Biology; Postdoctoral Associate, Duke University, Department of Anesthesiology; Graduate Researcher, Yale University, Department of Molecular Biophysics & Biochemistry. Areas of Interest: Cellular and Molecular Neuroscience, Drosophila genetics and behavior, Sensory Neurobiology, Microscopy and imaging, Nociception and chronic pain.

There are 9 included publications by Dr. Andrew Bellemer :

TitleDateViewsBrief Description
Egg Laying Decisions In Drosophila Are Consistent With Foraging Costs Of Larval Progeny 2012 120 Decision-making is defined as selection amongst options based on their utility, in a flexible and context-dependent manner. Oviposition site selection by the female fly, Drosophila melanogaster, has been suggested to be a simple and genetically tract...
An Evolutionary Conserved Switch In Response To GABA Affects Development And Behavior Of The Locomotor Circuit Of Caenorhabditis elegans 2015 135 The neurotransmitter gamma-aminobutyric acid (GABA) is depolarizing in the developing vertebrate brain, but in older animals switches to hyperpolarizing and becomes the major inhibitory neurotransmitter in adults. We discovered a similar developmenta...
Gaq And Phospholipase Cß Signaling Regulate Nociceptor Sensitivity In Drosophila melanogaster Larvae 2018 118 Drosophila melanogaster larvae detect noxious thermal and mechanical stimuli in their environment using polymodal nociceptor neurons whose dendrites tile the larval bodywall. Activation of these nociceptors by potentially tissue-damaging stimuli elic...
Photostimulation Alters c-Fos Expression In The Dorsal Raphe Nucleus 2005 727 Retinal afferents to the dorsal raphe nucleus (DRN) have been described in a number of species, including Mongolian gerbils, but functional correlates of this optic pathway are unknown at present. To determine whether temporally modulated photostimul...
The Possium Chloride Cotransporter KCC-2 Coordinates Development Of Inhibitory Neurotransmission And Synapse Structure In Caenorhabditis elegans 2009 121 Chloride influx through GABA-gated chloride channels, the primary mechanism by which neural activity is inhibited in the adult mammalian brain, depends on chloride gradients established by the potassium chloride cotransporter KCC2. We used a genetic ...
Sensory Neuron Sensitivity In Drosophila Melanogaster Is Regulated By Translation Initiation Factors 2019 241 Millions of Americans suffer from chronic pain each year, and pain symptoms are the leading cause of hospitalization and long-term disability. A significant hurdle for our understanding of pain syndromes is an incomplete appreciation of the cellular,...
Thermosensory And Nonthermosensory Isoforms Of Drosophila melanogaster TRPA1 Reveal Heat-Sensor Domains Of A ThermoTRP Channel 2011 112 Specialized somatosensory neurons detect temperatures ranging from pleasantly cool or warm to burning hot and painful (nociceptive). The precise temperature ranges sensed by thermally sensitive neurons is determined by tissue-specific expression of i...
Thermotaxis, Circadian Rhythms, And TRP Channels In Drosophila 2015 118 The fruit fly Drosophila melanogaster is a poikilothermic organism that must detect and respond to both fine and coarse changes in environmental temperature in order maintain optimal body temperature, synchronize behavior to daily temperature fluctua...
Two Types Of Chloride Transporters Are Required For GABAA Receptor-Mediated Inhibition In C. elegans 2011 113 Chloride influx through GABA-gated Cl- channels, the principal mechanism for inhibiting neural activity in the brain, requires a Cl- gradient established in part by K+–Cl- cotransporters (KCCs). We screened for Caenorhabditis elegans mutants defectiv...