New terpenoids from the corticioid fungus Punctularia atropurpurascens and their antimycobacterial evaluation

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Mario Figueroa Saldivar, Adjunct Faculty (Creator)
Shabnam Hematian, Assistant Professor (Creator)
Firoz Shah Tuglak Khan, Postdoctoral Research Associate (Creator)
Huzefa A. Raja, Research Scientist (Creator)
Institution
The University of North Carolina at Greensboro (UNCG )
Web Site: http://library.uncg.edu/

Abstract: Chemical investigation of Punctularia atropurpurascens strain HM1 (Punctulariaceae), a corticioid isolated from a decorticated piece of Quercus bark collected in Bosque de Tlalpan, Mexico City, led to the isolation of a new drimane, 1-a-hydroxy-isodrimenine (1) and a new tetrahydroxy kauranol, 16-hydroxy-phlebia-nor-kauranol (2), together with the known N-phenylacetamide (3). Structures of all compounds were elucidated by spectroscopic and spectrometric methods, and the absolute configuration of 1 and 2 was confirmed via single-crystal X-ray crystallography. The isolated compounds showed modest antimycobacterial activity.

Additional Information

Publication
Planta Medica. 2022. https://doi.org/10.1055/a-1786-8072
Language: English
Date: 2022
Keywords
Punctularia atropurpurascens, corticioid, drimane, nor-kaurane, antitubercular activity, Punctulariaceae

Email this document to