Applications of ion-selective electrodes

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Joseph J. Guanci (Creator)
The University of North Carolina at Greensboro (UNCG )
Web Site:
Harvey Herman

Abstract: The development of a thiamine (vitamin B1) ion-selective electrode has been investigated. The particular type of electrode employed was a liquid membrane electrode composed of an ion-exchanger solution consisting of thiamine-bromothymol blue acid dye salt in a water immiscible solvent one-half octanol-1, one-half chloroform. Several properties of the thiamine liquid membrane electrode were studied: response, reproducibility, and pH dependence. The primary purpose of the thiamine electrode was to determine the concentration of thiamine commonly found in commercially available multi-vitamin preparations. The thiamine electrode was tested in the presence of diverse substances normally found in these vitamin preparations. These interference substances were vitamin B6, (pyridoxine monohydrochloride), vitamin B2 (riboflavin), vitamin C (ascorbic acid), vitamin B3 (nicotinamide), and vitamin B5. (d-calcium pantothenate). Because of the large number of standard routine samples needed to be analyzed when determining the potential response of ion-selective electrodes, a hard-wire automatic solution addition instrument has been developed which handles addition of a stock solution to desired volumes either by manual control or by an automatic control. In conjunction with this unit, a data recording system was devised to store the electrical potential readings of the electrode cell for the different concentration ranges studied.

Additional Information

Language: English
Date: 1976
Electrodes, Ion selective
Vitamin B1

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