Cytochrome analysis of a cytoplasmic mutant of neurospora crassa

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Julian Wade Farrior (Creator)
The University of North Carolina at Greensboro (UNCG )
Web Site:
William Bates

Abstract: Much insight into the structure and function of genes has been obtained through the comparison of the wild type gene with its mutant allele. The only mutations that could be studied were those that resulted in identifiable phenotypic changes (markers). Nuclear chromosomes have been well characterized through those genetic markers which occurred as either the primary or secondary effects of mutation. Cytoplasmic inheritance has not been characterized as clearly as nuclear inheritance due to a shortage of available mutants and a lack of suitable genetic markers. Various cytoplasmic mutants of the filamentous fungus Neurospora crassa have provided some insight into cytoplasmic inheritance. The phenotypic expression of these mutations was typically a changed pattern of growth and a change in cytochrome concentration and distribution due to alterations in the mitochondria. By the use of these characteristic markers, successive stages may be observed in the phenotypic change produced in wild type cells by the micro-injection of [mi-l] mitochondria.

Additional Information

Language: English
Date: 1971
Neurospora crassa
Neurospora crassa $x Growth
Neurospora crassa $x Microbiology

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