Mealtime food intake and behavior of normal weight adult males : effects of phenylalanine and aspartame

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Milly Ryan-Harshman (Creator)
The University of North Carolina at Greensboro (UNCG )
Web Site:
Lucille Wakefield

Abstract: Two experiments were conducted to investigate the neurobehavioral effects of phenylalanine (PHE; 0.84, 2.52, 5.04, and 10.08 g) and aspartame (APM; 5.04 and 10.08 g) on energy and macronutrient selection and on subjective feelings of hunger, mood and arousal in normal weight adult males. Neither PHE nor APM altered mean energy intakes or macronutrient selection during lunch which began 60 or 105 min after the amino acids were consumed. During this time, increased (p < .05) visual analog scale scores for emptiness, rumbling, weakness, degree of hunger and urge to eat were found in both experiments, but no treatment effects or interactions were seen for any variable in either experiment. Plasma amino acid levels were measured after capsule administration at 45 min in experiment 1 and at 90 min in experiment 2 and were compared to baseline samples. Plasma PHE levels and ratios to other large neutral amino acids (NAA) rose significantly (p < .05) after all treatments except 0.84 g PHE; plasma tyrosine (TYR) levels increased (p < .05) only when greater than 2.52 g PHE was given. TYR/NAA ratios were higher (p < .05) after 2.52 and 5.04 g PHE, and 10.08 g APM. No relationships were found between food intake and plasma amino acid levels.

Additional Information

Language: English
Date: 1987
Men $x Nutrition
Men $x Physiology

Email this document to