The highly preorganized ligand 2, 9-DI-(2'-PYRIDYL)-1, 10-Phenanthroline, and its complexation properties with metal ions
- UNCW Author/Contributor (non-UNCW co-authors, if there are any, appear on document)
- Gregory Mercer Cockrell (Creator)
- Institution
- The University of North Carolina Wilmington (UNCW )
- Web Site: http://library.uncw.edu/
- Advisor
- Robert Hancock
Abstract: The compound 2,9-di-(2’-pyridyl)-1,10-phenanthroline (DPP) has many potential
uses in the fields of medicinal and environmental chemistry. The great stability
possessed by complexes of DPP and heavier metal ions such as cadmium, lead, and
mercury, is ideal when designing ligands for uses as fluorescence sensors or chelation
therapies. This ligand, and others in its class, posses a high degree of preorganization.
This means that they are designed to target specific metal ions by being in the correct
conformation in its free form. UV/Vis spectroscopy was utilized to calculate stability
constants with several different metal ions of varying ionic charges and radii. DPP was
found to be highly selective for cadmium with a log K1 = 12.21. Other metal ions that
formed very stable complexes were bismuth (log K1 = 15.72) and mercury (not
measurable with available materials). Fluorescence studies were conducted and found
that upon binding to cadmium, DPP has a dramatic increase in fluorescence intensity.
Fluorescence studies also showed that cadmium could be detected in aqueous solution at
concentrations as low as 1 x 10-10 M.
The highly preorganized ligand 2, 9-DI-(2'-PYRIDYL)-1, 10-Phenanthroline, and its complexation properties with metal ions
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Created on 1/1/2009
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Additional Information
- Publication
- Thesis
- A Thesis Submitted to the University of North Carolina at Wilmington in Partial Fulfillment of the Requirement for the Degree of Masters of Science
- Language: English
- Date: 2009
- Keywords
- Ligands--Synthesis, Metal ions--Analysis, Metals--Analysis
- Subjects
- Ligands -- Synthesis
- Metal ions -- Analysis
- Metals -- Analysis