Clinical use of rifampicin during routine reporting of rifampicin susceptibilities: a lesson in selective reporting of antimicrobial susceptibility data

ECU Author/Contributor (non-ECU co-authors, if there are any, appear on document)

RM Morrell (Creator)

CH Steffee (Creator)

BL Wasilauskas (Creator)

Institution

East Carolina University (ECU )

Web Site: http://www.ecu.edu/lib/

Abstract: Increased use of rifampicin for in-patients was noted after the laboratory began reporting rifampicin susceptibilities routinely for all Gram-positive bacterial isolates. The appropriateness of rifampicin use was evaluated by chart review for in-patients administered rifampicin during two time periods, before and during routine rifampicin susceptibility reporting, respectively. While rifampicin susceptibility was reported routinely, four patients were subjected to potentially harmful misuse of rifampicin. These findings reconfirm the necessity of interdepartmental consultation and extensive staff education whenever a modification of antimicrobial susceptibility profile reporting is contemplated. Furthermore, they underscore the role of the clinical microbiology laboratory in guiding antimicrobial therapy through limited reporting of susceptibility data.

Additional Information

Publication

Other

Language: English

Date: 2023

Subjects

rifampin consultation gram-positive bacteria gram-positive bacterial infections gram-positive cocci gram-positive rods time factors microbiology antimicrobials antimicrobial susceptibility appropriateness medical records review

Email this document to