Cardiac amyloidosis: A case report and review of literature

ECU Author/Contributor (non-ECU co-authors, if there are any, appear on document)

Adeyemi Adedamola,Alapati,Lavanya,Movahed,Assad Taiwo (Creator)

Institution

East Carolina University (ECU )

Web Site: http://www.ecu.edu/lib/

Abstract: BACKGROUNDCardiac amyloidosis, a disease caused by the precipitation of amyloid proteins inthe myocardial extracellular matrix has been historically difficult to diagnose dueto lack of specific clinical manifestations and necessity of biopsy to demonstrateamyloid deposition. However, advances in cardiovascular imaging techniqueshave facilitated earlier recognition of this disease. In addition, while once thoughtof as incurable, treatment strategies are emerging for cardiac amyloidosis,making early diagnosis essential.CASE SUMMARYWe outline the case of a 73 years old African American female who was admittedwith sudden onset shortness of breath and found to be in cardiogenic shock.Cardiac amyloidosis was suspected due to discordance betweenelectrocardiogram and echocardiogram findings and this was subsequentlyconfirmed with the aid of scintigraphy and an endomyocardial biopsy.CONCLUSIONOur objective is to highlight the diagnostic evaluation and clinical implications ofcardiac amyloidosis.

Additional Information

Publication

Other

Language: English

Date: 2019

Keywords

Cardiac amyloidosis; Restrictive cardiomyopathy; Transthyretin; Case report

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