The effect of race and chronic obstructive pulmonary disease on long-term survival after coronary artery bypass grafting

ECU Author/Contributor (non-ECU co-authors, if there are any, appear on document)

Jimmy Thomas,O'Neal,Wesley T.,Anderson,Curtis A.,O'Neal, Efird (Creator)

Institution

East Carolina University (ECU )

Web Site: http://www.ecu.edu/lib/

Abstract: Background: Chronic obstructive pulmonary disease (COPD) is a known predictor of decreased long-term survival after coronary artery bypass grafting (CABG). Differences in survival by race have not been examined.Methods: A retrospective cohort study was conducted of CABG patients between 2002 and 2011. Long-term survival was compared in patients with and without COPD and stratified by race. Hazard ratios (HR) and 95% confidence intervals (CI) were computed using a Cox regression model.Results: A total of 984 (20%) patients had COPD (black n = 182; white n = 802) at the time of CABG (N = 4,801). The median follow-up for study participants was 4.4 years. COPD was observed to be a statistically significant predictor of decreased survival independent of race following CABG (no COPD: HR = 1.0; white COPD: adjusted HR = 1.9, 95% CI = 1.7--2.3; black COPD: adjusted HR = 1.6, 95% CI = 1.1--2.2).Conclusion: Contrary to the expected increased risk of mortality among black COPD patients in the general population, a similar survival disadvantage was not observed in our CABG population.

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Publication

Other

Language: English

Date: 2013

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