Catabolite repression control (crc) gene and pseudomonas virulence
- ECU Author/Contributor (non-ECU co-authors, if there are any, appear on document)
- David Collier (Creator)
- Paul Hager (Creator)
- Paul Phibbs (Creator)
- Institution
- East Carolina University (ECU )
- Web Site: http://www.ecu.edu/lib/
Abstract: A method of screening for compounds that inhibit the virulence of Pseudomonas bacteria comprises the steps of: providing a culture medium comprising Pseudomonas bacteria; administering a test compound to said bacteria; and then detecting the presence or absence of inhibition of the catabolite repression control (Crc) protein in said bacteria , the inhibition of the Crc protein indicating said compound has antivirulence activity against Pseudomonas bacteria. Antivirulence compounds and the use thereof in treating Pseudomonas infections are also disclosed.
Additional Information
- Publication
- Other
- Language: English
- Date: 2002
- Keywords
- screening, Pseudomonas, Antivirulence
- Subjects
| Title | Location & Link | Type of Relationship |
| Catabolite repression control (crc) gene and pseudomonas virulence | http://hdl.handle.net/10342/7531 | The described resource references, cites, or otherwise points to the related resource. |