The Effect of Race and Chronic Obstructive Pulmonary Disease on Long-Term Survival after Coronary Artery Bypass Grafting

ECU Author/Contributor (non-ECU co-authors, if there are any, appear on document)

Curtis A. Anderson (Creator)

W. Randolph Chitwood (Creator)

Jimmy T. Efird (Creator)

T. Bruce Ferguson (Creator)

Linda C. Kindell (Creator)

Alan P. Kypson (Creator)

Wesley T. O’Neal (Creator)

Jason B. O’Neal (Creator)

Institution

East Carolina University (ECU )

Web Site: http://www.ecu.edu/lib/

Abstract: Background: Chronic obstructive pulmonary disease (COPD) is a known predictor of decreased long-term survival after coronary artery bypass grafting (CABG). Differences in survival by race have not been examined. Methods: A retrospective cohort study was conducted of CABG patients between 2002 and 2011. Long-term survival was compared in patients with and without COPD and stratified by race. Hazard ratios (HR) and 95% confidence intervals (CI) were computed using a Cox regression model. Results: A total of 984 (20%) patients had COPD (black n?=?182; white n?=?802) at the time of CABG (N?=?4,801). The median follow-up for study participants was 4.4?years. COPD was observed to be a statistically significant predictor of decreased survival independent of race following CABG (no COPD: HR?=?1.0; white COPD: adjusted HR?=?1.9, 95% CI?=?1.7–2.3; black COPD: adjusted HR?=?1.6, 95% CI?=?1.1–2.2). Conclusion: Contrary to the expected increased risk of mortality among black COPD patients in the general population, a similar survival disadvantage was not observed in our CABG population.

Additional Information

Publication

Other

Frontiers in Public Health; 1: p. 1-7

Language: English

Date: 2013

Keywords

survival, long-term, race, COPD, CABG

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