Pharmaceutically acceptable fixed-dried human blood platelets
- ECU Author/Contributor (non-ECU co-authors, if there are any, appear on document)
- Arthur P. Bode (Creator)
- Marjorie S. Read (Creator)
- Robert L. Reddick (Creator)
- Institution
- East Carolina University (ECU )
- Web Site: http://www.ecu.edu/lib/
Abstract: Fixed-dried human blood platelets and processes for preparing the same are disclosed. The platelets, upon reconstitution; adhere to thrombogenic surfaces; do not adhere to non-thrombogenic surfaces; undergo shape change (spreading) upon adhering to a thrombogenic surface; adhere to one another to form a hemostatic plug upon adhering to a thrombogenic surface; and release their granular contents. Pharmaceutical formulations containing the same are also disclosed. The platelets are preferably fixed by means of a fixative such as formaldehyde, paraformaldehyde, or glutaraldehyde, or fixed by means of a permanganate fixate. The platelets are preferably dried by lyophilization.
Additional Information
- Publication
- Other
- Language: English
- Date: 1999
| Title | Location & Link | Type of Relationship |
| Pharmaceutically acceptable fixed-dried human blood platelets | http://hdl.handle.net/10342/5203 | The described resource references, cites, or otherwise points to the related resource. |