William Durante

There are 3 included publications by William Durante :

TitleDateViewsBrief Description
Arginase Promotes Neointima Formation in Rat Injured Carotid Arteries 2011 61765 Objective—Arginase stimulates the proliferation of cultured vascular smooth muscle cells VSMCs); however the influence of arginase on VSMC growth in vivo is not known. This study nvestigated the impact of arginase on cell cycle progression and neoi...
The cyclic GMP modulators YC-1 and zaprinast reduce vessel remodeling through anti-proliferative and pro-apoptotic effects 2011 61765 Guanosine-specific cyclic nucleotide signaling is suggested to serve protective actions in the vasculature; however the influence of selective pharmacologic modulation of cyclic guanosine monophosphate (GMP)-synthesizing soluble guanylate cyclase (sG...
YC-1 Stimulates the Expression of Gaseous Monoxide-Generating Enzymes in Vascular Smooth Muscle Cells 2011 61765 The benzylindazole derivative 3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole (YC-1) is an allosteric stimulator of soluble guanylate cyclase (sGC) that sensitizes the enzyme to the gaseous ligands carbon monoxide (CO) and nitric oxide (NO). In t...