William H. Chappell

There are 3 included publications by William H. Chappell :

TitleDateViewsBrief Description
Roles of the RAF/MEK/ERK Pathway in Cell Growth Malignant Transformation and Drug Resistance 2011 690183 Growth factors and mitogens use the Ras/Raf/MEK/ERK signaling cascade to transmit signals from their receptors to regulate gene expression and prevent apoptosis. Some components of these pathways are mutated or aberrantly expressed in human cancer (e...
Targeting prostate cancer based on signal transduction and cell cycle pathways 2011 690183 Prostate cancer remains a leading cause of death in men despite increased capacity to diagnose at earlier stages. After prostate cancer has become hormone independent which often occurs after hormonal ablation therapies it is difficult to effectively...
Targeting the RAF/MEK/ERK PI3K/AKT and P53 pathways in hematopoietic drug resistance 2011 690183