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M,Milella,M,Ruvolo,P,Watts,JC,Ricciardi,MR,Korchin Konopleva
ECU
There are 1 included publications by M,Milella,M,Ruvolo,P,Watts,JC,Ricciardi,MR,Korchin Konopleva :
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Brief Description
MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex
2012
Recently, strategies for acute myeloid leukemia (AML) therapy have been developed that target anti-apoptotic BCL2 family members using BH3-mimetic drugs such as ABT-737. Though effective against BCL2 and [BCL-X.sub.L], ABT-737 poorly inhibits MCL-1. ...
