| Title | Date | Views | Brief Description |
|---|
| Effects of Dietary Leucine Supplementation on Muscle Mass and Markers of Protein Degradation in Overloaded Skeletal Muscles of Young Adult and Aged Rats |
2012 |
688479 |
The hypertrophic response to overload in fast-twitch skeletal muscle is impaired in aged humans and rats and upregulation of protein degradation pathways are hypothesized to be a contributing factor. Muscle growth occurs when protein synthesis is gre... |
| Paired Effects of Dietary Leucine Supplementation and Overload on Protein Translational Signaling and Hypertrophy in Aged Rat Skeletal Muscle |
2013 |
688479 |
Sarcopenia is an age-associated disorder that causes loss of skeletal muscle mass particularly in type II (fast-twitch) muscle fibers. This loss in muscle mass can cause disability reductions in the quality of life and can contribute to the developme... |
| Skeletal Muscle Eukaryotic Elongation Factor 2 (eEF2) Response to Acute Resistance Exercise in Young and Old Men and Women : Relationship to Muscle Glycogen Content and 5'-AMP-Activated Protein Kinase (AMPK) Activity |
2011 |
688479 |
Sarcopenia is associated with an age-related decrease in skeletal muscle mass which can result in decreases in strength and physical functioning in the older population. Resistance training interventions are not completely effective in stimulating mu... |
| Skeletal Muscle Forkhead Box 3A (FOXO3A) Response to Acute Resistance Exercise in Young and Old Men and Women : Relationship to Muscle Glycogen Content and 5'-AMP Activated Protein Kinase (AMPK) Activity |
2011 |
688479 |
In addition to suppressing protein synthesis 5'-AMP-activated protein kinase (AMPK) stimulates muscle protein degradation through forkhead box transcription factor 3A (FOXO3A) known to promote transcription of mRNAs encoding degradation pathway prote... |
| Cleaved Caspase-3 Response to Acute Resistance Exercise in Young and Old Men and Women : Relationship to Muscle Glycogen Content and 5'-AMP-Activated Protein Kinase (AMPK) Activity |
2011 |
688479 |
In addition to suppressing protein synthesis and activating protein degradation in skeletal muscle and other cell types 5'-AMP-activated protein kinase (AMPK) is known to stimulate nuclear apoptosis in non-muscle cells through cleaved (activated) cas... |