Isolation and characterization of secondary metabolites from Eupatorium serotinum
- WCU Author/Contributor (non-WCU co-authors, if there are any, appear on document)
- Timothy James Willis (Creator)
- Institution
- Western Carolina University (WCU )
- Web Site: http://library.wcu.edu/
- Advisor
- Jason Clement
Abstract: A phytochemical investigation into the species Eupatorium serotinum
(Boneset), which is native to the mountains of western North Carolina, was
conducted. The isolation of three secondary metabolites from Eupatorium
serotinum was accomplished by a modified Kupchan method and various
chromatographic seperations. Various standard and correlation NMR techniques
were used to determine the identity of these compounds. The compounds
discovered were 4-aromadendren-3-one, 7d-methoxy-4(14)-oppositen-1ß-ol, and
germacra-4(15),5,10(14)-trien-1ß-ol. These compounds were newly discovered in
Eupatorium serotinum, but all have been found in other species before. Two of
these compounds have been found in various members of the aster family, of
which Eupatorium serotinum is from, and may have use as biomarkers.
Isolation and characterization of secondary metabolites from Eupatorium serotinum
PDF (Portable Document Format)
7089 KB
Created on 3/1/2012
Views: 19841
Additional Information
- Publication
- Thesis
- Language: English
- Date: 2012
- Keywords
- Eupatorium serotinum, Natural Products Chemistry, Phytochemistry
- Subjects
- Eupatorium -- Metabolism
- Eupatorium -- Composition