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Theses & Dissertations


Summers, Jack


There are 3 item/s.

TitleDateViewsBrief Description
Superoxide dismutase inhibitor screening and characterization using ¹?F NMR 2010 1465 Superoxide dismutase enzymes (SOD) catalyze the disproportionation of superoxide to form molecular oxygen and hydrogen peroxide in a cyclic mechanism. SODs prevent the formation of hydroxyl radicals, preventing apoptosis. Up-regulation of this enzy...
Characterization of inhibitors for Cu/Zn superoxide dismutase observed by ¹?F NMR methods 2010 1132 Superoxide dismutase (SOD) is an enzyme that disproportionates superoxide (O2-) into H2O2 and O2. The inhibition of this enzyme could be a novel method for the treatment of chronic diseases such as leukemia, cancer and malaria.2,7,8 Methods that rely...
Studies on superoxide dismutase inhibition and application of methods to study metal ion participation in complication of diabetes 2012 452 Studies on Superoxide Dismutase Inhibition We used NMR relaxation rates to study reactions of the enzyme superoxide dismutase (SOD) with low molecular weight polyphenolic compounds. While the compounds appeared to inhibit SOD, we discovered eviden...