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Theses & Dissertations


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Halkides, Christopher


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TitleDateViewsBrief Description
Crystallization of phosphono-CheY from Thermotoga maritima 2009 1212 An analog to the active form of the signal transduction protein CheY is produced, purified, and crystallized herein. The analog, which was named phosphono-CheY, is synthesized to mimic the in vivo active form of CheY known as P-CheY; P-CheY only h...
Synthesis and characterization of phosphono-CheY from Thermotoga maritima 2009 639 The chemical and molecular mechanisms of bacterial chemotaxis have been extensively characterized through structural studies of mutant chemotaxis proteins. CheY~P (the active, signaling form of CheY) binds the switch protein FliM at the intracellul...