Selective Formation of 1,5-Substituted Sulfonyl Triazoles Using Acetylides and Sulfonyl Azides
- UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
- Mitchell Croatt, Assistant Professor (Creator)
- Maria Elena Meza-Avina, Research Scientist (Contributor)
- Institution
- The University of North Carolina at Greensboro (UNCG )
- Web Site: http://library.uncg.edu/
Abstract: The reaction of acetylides with sulfonyl azides was found to selectively form 1,5-substituted sulfonyl triazoles. This reaction thus provides access to the regioisomeric product as compared to the popular copper-catalyzed azide–alkyne cycloaddition. The reaction is efficient and selective with a variety of alkyne sources and sulfonyl azides and can incorporate an additional electrophile to yield 1,4,5-trisubstituted sulfonyl triazoles.
Selective Formation of 1,5-Substituted Sulfonyl Triazoles Using Acetylides and Sulfonyl Azides
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Created on 3/21/2013
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Additional Information
- Publication
- Language: English
- Date: 2011
- Keywords
- chemistry, biochemistry, sulfonyl triazoles, acetylides, solfonyl aziders