Hypervalent Iodonium Alkynyl Triflate Generated Phenylcyanocarbene and Its Reactivity with Aromatic Systems

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Mohammed Al-Huniti, Research Scientist (Creator)
Mitchell Croatt, Assistant Professor (Creator)
Institution
The University of North Carolina at Greensboro (UNCG )
Web Site: http://library.uncg.edu/

Abstract: Phenylcyanocarbene was generated by the reaction of azide with a hypervalent iodonium alkynyl triflate and reacted in situ with 21 different carbocyclic and heterocyclic aromatic compounds. These reactions led to more complex products that frequently underwent subsequent rearrangements. The reactivity was further explored in a mechanistic study to ascertain the chemoselectivity and stereospecificity.

Additional Information

Publication
Journal of Organic Chemistry 2017, 82, 11772-11780
Language: English
Date: 2017
Keywords
reactions, phenylcyanocarbene, chemoselectivity, stereospecificity

Email this document to