Direct wiring of cytochrome c's heme unit to an electrode: Electrochemical studies
- UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
- Jianjun Wei, Associate Professor (Creator)
- Institution
- The University of North Carolina at Greensboro (UNCG )
- Web Site: http://library.uncg.edu/
Abstract: [Image displayed in pdf]
A novel strategy for the immobilization of cytochrome c on the surface of chemically modified electrodes is demonstrated and used to investigate the protein's electron-transfer kinetics. Mixed monolayer films of alkanethiols and ?-terminated alkanethiols (terminated with pyridine, imidazole, or nitrile groups that are able to ligate with the heme) are used to adsorb cytochrome c to the surface of gold electrodes. The use of mixed films, as opposed to pure films, allows the concentration of adsorbed cytochrome to remain dilute and ensures a higher degree of homogeneity in their environment. The adsorbed protein is studied using electrochemical methods and scanning tunneling microscopy.
Direct wiring of cytochrome c's heme unit to an electrode: Electrochemical studies
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Additional Information
- Publication
- Journal of the American Chemical Society, 2002, 124 (32), 9591-9599.
- Language: English
- Date: 2002
- Keywords
- cytochrome c, chemically modified electrodes, electron transfer, protein