Operant Discrimination Learning and Operant Bar-Pressing Rates in Inbred and Heterogeneous Laboratory Mice

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Douglas Wahlsten, Visiting Professor (Creator)
Institution
The University of North Carolina at Greensboro (UNCG )
Web Site: http://library.uncg.edu/

Abstract: Mice from four inbred strains and a heterogeneous line were first reduced to 90% of their ad libitum body weight and were then trained to press a bar to obtain food pellets. After 9 days of training with a continuous schedule of reinforcement (CRF), mice were required to discriminate between conditions of reward and nonreward as indicated by a tone and a light; discrimination training continued for 21 days. Considerable genetic variation was apparent for asymptotic pressing rates under CRF as well as discrimination performance. However, the highest discrimination ratios were achieved by mice with the lowest pressing rates. Results are discussed in terms of associative and nonassociative processes which may contribute to genetic variation in performance on learning tasks.

Additional Information

Publication
Behavior Genetics, 1974, 4, 383-393.
Language: English
Date: 1974
Keywords
Operant conditioning, Strains, Mice, Learning