Synthesis of Novel Platinum Complexes Showing Potential as Anti-Cancer Drugs

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Terence "Terry" Nile, Professor (Creator)
The University of North Carolina at Greensboro (UNCG )
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Abstract: Many metal co-ordination complexes have been investigated as potential anti-cancer drugs with a rich diversity of effects and toxicity (1). One of the most successful is cis-diamminedichloroplatinum(II), which is an active anti-tumor agent at low concentration. Many complexes containing a variety of amines have been synthesized and tested, again with a wide range of effectiveness (1). We wish to report the synthesis of five new platinum complexes and the results of preliminary screening for potential anti-cancer activity.

Additional Information

Inorganic and Nuclear Chemistry Letters, 15, 183 (1979).
Language: English
Date: 1979
platinum complexes, anti-cancer drugs, anti-tumor agents, anti-cancer activity

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