Improving Education Provided to Patients on the Interaction of Sugammadex and Hormonal

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Laila Jefferson (Creator)
Institution
The University of North Carolina at Greensboro (UNCG )
Web Site: http://library.uncg.edu/
Advisor
Stacey Schlesinger

Abstract: Background: Sugammadex is a medication used to rapidly reverse the effects of rocuronium and vecuronium by encapsulating and physiologically inactivating it. Although sugammadex has a high affinity for rocuronium and vecuronium, it can also encapsulate progesterone and estrogen, thereby decreasing the effectiveness of progesterone hormonal contraceptives and increasing the risk of unintended pregnancy. It is recommended that patients on hormonal contraceptives use a non-hormonal birth control backup method for seven days after receiving sugammadex. Approximately 65% of women of reproductive age in the United States are currently using some form of hormonal contraception (CDC, 2020). The percentage of ambulatory surgical cases specifically performed on women also increased by 1.1% between the years 2000 and 2014 (CDC, 202). This increase in the utilization of sugammadex and increase in female surgical cases suggests that the number of patients affected by this medication interaction will likely continue to increase. Patients on hormonal contraceptives who receive sugammadex perioperatively are provided education on this interaction, however, this education is routinely provided postoperatively, following the administration of anesthesia. Following anesthesia, a patient’s memory may be impaired, and they may not remember the instructions provided. Providing patient education preoperatively improves patient recall. Purpose: The purpose of this quality improvement project was to improve patient?recall of provided education on the interaction of sugammadex and hormonal contraceptives by having anesthesia providers provide this education prior to the administration of anesthetic medications. Methods: Patients using hormonal contraceptives that were anticipated to receive sugammadex perioperatively were provided patient education by an anesthesia provider preoperatively in addition to routine postoperative instructions provided by the nursing staff. Patients on hormonal contraceptives that received sugammadex were contacted postoperatively by phone to assess their recall of provided education. Results: Thirty-three percent of patients receiving postoperative instructions only on the interaction of sugammadex and hormonal contraceptives were able to recall receiving that education. In patients also provided this education preoperatively, 23% were able to recall receiving that education. Recommendations and Conclusion: Patient education provided preoperatively by the anesthesia provider did not improve patient recall of receiving this education. Further study is recommended to determine the best method(s) of educating patients on the implications of the interaction between sugammadex and hormonal contraceptives.

Additional Information

Publication
Other
Language: English
Date: 2024
Keywords
sugammadex, preoperative teaching, hormonal contraceptives

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