Letter to the editor: Bias in the measurement of bias. Letter regarding 'Citation bias and selective focus on positive findings in the literature on the serotonin transporter gene (5-HTTLPR), life stress and depression'

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Suzanne Vrshek-Schallhorn, Associate Professor and Undergraduate Program Director (Creator)
Institution
The University of North Carolina at Greensboro (UNCG )
Web Site: http://library.uncg.edu/

Abstract: de Vries et al. (2016) argue that discussion of the 5-HTTLPR-stress gene-environment interaction (G × E) (Caspi et al. 2003) is more positive than merited because authors often cast negative results as positive in abstracts, and negative papers with positive focus are differentially cited. These bold claims deserve careful scrutiny. Four methodological choices we highlight bias their primary results; the vast majority of papers disclose mixed and negative results in their abstracts (Table 1). Further, even if positive focus was prevalent, it could not bias meta-analytic results. The field can best move forward by ameliorating environmental measurement.

Additional Information

Publication
Psychological Medicine, 47(1)
Language: English
Date: 2016
Keywords
measurement, serotonin, life stress, bias, serotonin transporter, psychiatry, stress, depression

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