The Influence Of Sex-Specific Hormones On Flow Mediated Dilation And Passive Limb Movement
- ASU Author/Contributor (non-ASU co-authors, if there are any, appear on document)
- Laurel Kaitlyn Koontz (Creator)
- Institution
- Appalachian State University (ASU )
- Web Site: https://library.appstate.edu/
- Advisor
- Stephen Ratchford
Abstract: Vascular health is affected by sex-specific hormones: estrogen, progesterone, and testosterone. There are two tests that noninvasively assess endothelial function and vascular function: Flow Mediated Dilation and Passive Limb Movement. We hypothesize that 1) Natural menstrual cycle women will display greater fluctuations in %FMD and PLM throughout one month than women using systemic hormonal contraceptives or than age-matched men. 2) Systemic hormonal contraceptive women will display no significant fluctuations in %FMD and PLM, as compared to age-matched men 3) Healthy age-matched men to have no significant difference in % FMD results compared to women on a natural menstrual cycle and compared to women using systemic hormonal contraceptive. The primary study aim is to conduct a literature review of the following topics: vascular blood flow and regulation, endothelial cells, vascular smooth muscle cells, dysfunction in endothelial cells, and vascular smooth muscle cells leading to health-related decrements, the influence of sex-specific hormones, the menstrual cycle, menopause, and the influence of systemic hormonal contraceptives on vascular blood flow regulation.
The Influence Of Sex-Specific Hormones On Flow Mediated Dilation And Passive Limb Movement
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Created on 1/13/2022
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Additional Information
- Publication
- Thesis
- Koontz, L. (2021). The Influence Of Sex-Specific Hormones On Flow Mediated Dilation And Passive Limb Movement. Unpublished Master’s Thesis. Appalachian State University, Boone, NC.
- Language: English
- Date: 2021
- Keywords
- Vascular Function,
Sex-specific Hormones,
Menstrual Cycle,
Flow Mediated Dilation,
Passive Limb Movement