Construction of realistic hybrid computational fetal phantoms from radiological images in three gestational ages for radiation dosimetry applications

ECU Author/Contributor (non-ECU co-authors, if there are any, appear on document)

Rasha,Nelson,Keith,Zaidi,Habib,Dingfelder,Michael Makkia (Creator)

Institution

East Carolina University (ECU )

Web Site: http://www.ecu.edu/lib/

Abstract: Radiation exposure and associated radiation risks are major concerns for fetal development forpregnant patients who undergo radiation therapy or diagnostic imaging procedures. In order toaccurately estimate the radiation dose to the fetus and assess the uncertainty of fetal position androtation, three hybrid computational fetus phantoms were constructed using magnetic resonanceimaging (MRI) for each fetus model as a starting point to construct a complete anatomically accuratefetus, gravid uterus, and placenta. A total of 27 fetal organs were outlined from radiological imagesvia the Velocity Treatment Planning System. The DICOM-Structure set was imported to Rhinocerossoftware for further reconstruction of 3D fetus phantom model sets. All fetal organ masses werecompared with ICRP-89 reference data. Our fetal model series corresponds to 20, 31, and 35 weeks ofpregnancy, thus covering the second and third trimester. Fetal positions and locations were carefullyadapted to represent the real fetus locations inside the uterus for each trimester of pregnancy. Thenew series of hybrid computational fetus models together with pregnant female models can be usedin evaluating fetal radiation doses in diagnostic imaging and radiotherapy procedures.

Additional Information

Publication

Other

Language: English

Date: 2019

Keywords

hybrid phantoms, fetus, segmentation, 3D modeling, NURBS, radiation dosimetry

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