Real-time compression feedback for patients with in-hospital cardiac arrest: a multi-center randomized controlled clinical trial

ECU Author/Contributor (non-ECU co-authors, if there are any, appear on document)

Farshid R. Bashar (Creator)

Behrooz Farzanegan (Creator)

Reza Goharani (Creator)

Keivan Gohari-Moghaddam (Creator)

Mohammadreza Hajiesmaeili (Creator)

Sevak Hatamian (Creator)

Mohammad A. Khabiri Khatir (Creator)

Masoum Khoshfetrat (Creator)

Seyed J. Madani (Creator)

Andrew C. Miller (Creator)

Seyed M. M. Mosavinasab (Creator)

Seyedpouzhia Shojaei (Creator)

Amir Vahedian-Azimi (Creator)

Institution

East Carolina University (ECU )

Web Site: http://www.ecu.edu/lib/

Abstract: Abstract Objective To determine if real-time compression feedback using a non-automated hand-held device improves patient outcomes from in-hospital cardiac arrest (IHCA). Methods We conducted a prospective , randomized , controlled , parallel study (no crossover) of patients with IHCA in the mixed medical-surgical intensive care units (ICUs) of eight academic hospitals. Patients received either standard manual chest compressions or compressions performed with real-time feedback using the Cardio First Angel„¢ (CFA) device. The primary outcome was sustained return of spontaneous circulation (ROSC) , and secondary outcomes were survival to ICU and hospital discharge. Results One thousand four hundred fifty-four subjects were randomized; 900 were included. Sustained ROSC was significantly improved in the CFA group (66.7% vs. 42.4% , P€‰<€‰0.001) , as was survival to ICU discharge (59.8% vs. 33.6%) and survival to hospital discharge (54% vs. 28.4% , P€‰<€‰0.001). Outcomes were not affected by intra-group comparisons based on intubation status. ROSC , survival to ICU , and hospital discharge were noted to be improved in inter-group comparisons of non-intubated patients , but not intubated ones. Conclusion Use of the CFA compression feedback device improved event survival and survival to ICU and hospital discharge. Trial registration The study was registered with Clinicaltrials.gov ( NCT02845011 ) , registered retrospectively on July 21 , 2016.

Additional Information

Publication

Other

Journal of Intensive Care. 2019 Jan 22;7(1):5

Language: English

Date: 2019

Keywords

CPR, Resuscitation, Chest compression, Cardio First Angel, Critical care, Intensive care

Subjects

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