HPLC Method Validation: A Global Application for the Analysis of Amoxicillin

UNCP Author/Contributor (non-UNCP co-authors, if there are any, appear on document)

Ethan Williamson (Creator)

Institution

The University of North Carolina at Pembroke (UNCP )

Web Site: http://www.uncp.edu/academics/library

Advisor

Meredith Storms

Abstract: Several factors can determine the purity and efficacy of certain pharmaceutical compounds. These environmental factors play a huge role in how drug manufacturers store and handle compounds. Several countries that are without resources such as dependable electricity and clean water, also suffer from not receiving proper healthcare, which includes not receiving correct medication. The main goal of this research is to validate the HPLC method which will be used to analyze the purity of amoxicillin capsules collected from selected African countries to show the importance of safe and effective pharmaceutical products. Before the samples can be analyzed, it is necessary to meet several criteria for a validated HPLC method. Thus, the aim of this research is to demonstrate the linearity of the HPLC method as well as to show that the method meets the requirements for tailing factor and column efficiency.

HPLC Method Validation: A Global Application for the Analysis of Amoxicillin
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Created on 5/2/2019
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Additional Information

Publication

Honors Project

Esther G. Maynor Honors College

Language: English

Date: 2019

Keywords

HPLC method, Amoxicillan, pharmaceutical purity

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