Effect of age and thirty minutes of exercise on prostacyclin/thromboxane A ratios and circulating concentrations of prostacyclin and thromboxane A

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Mikel Kent Todd (Creator)
The University of North Carolina at Greensboro (UNCG )
Web Site: http://library.uncg.edu/
Allan H. Goldfarb

Abstract: The effect thirty minutes of treadmill exercise on prostacyclin/thromboxane A2 (PGI2/TXA2) ratios, plasma PGI2 and TXA2 in young and older men, 27.8 ± 0.8 and 55.4 ± 1.3 years old, respectively, was determined. Exercise intensity was maintained at 70-75% of V02max. Venipuncture samples were taken at rest, immediately after exercise, and at thirty minutes recovery. Total cholesterol (TC), high density lipoprotein (HDL), and low density lipoprotein (LDL) were determined from a serum sample taken at rest. Plasma 6-ketoprostaglandin F1 and TXB2 (i.e. stable metabolites of PGI2 and TXA2 respectively) were determined by radioimmunoassay. Plasma PGI2 and TXA2 were corrected for hemoconcentration; TXA2 was corrected for platelet count. Linoleic acid (LLA) intake and polyunsaturated/saturated fat ratios (P/S ratios) were estimated by four-day diet records.

Additional Information

Language: English
Date: 1990
Exercise $x Physiological aspects

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